| Details: | |
| Tested Applications | ELISA, WB | 
| Target Information | Murine FBXL5 is a 77.9kDa protein that plays a central role in iron homeostasis. | 
| Product Format | Affinity Purified | 
| Alternate Names | F-box/LRR-repeat protein 5, F-box and leucine-rich repeat protein 5, F-box protein FBL4/FBL5, p45SKP2-like protein, FBL4, FBL5, FLR1 | 
| Clone | 3F5G12G9 | 
| Host | Mouse | 
| Isotype | IgG2b | 
| Immunogen | Recombinant Protein | 
| Epitope | Unknown | 
| Relevance | Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued | 
| Specificity | Mouse | 
| Reported Reactivity | Unknown | 
| Reported Applications | Unknown | 
			
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