| Details: | |
| Tested Applications | WB, ELISA | 
| Target Information | A is a 35 kDa subunit of Shiga Toxin | 
| Product Format | Affinity Purified | 
| Alternate Names | SLT-2 A subunit, SLT-2a, SLT-IIa, Verocytotoxin 2 subunit A, Verotoxin 2 subunit A, rRNA N-glycosidase 2, stxA2, stx2A | 
| Clone | 1C6A6G9 | 
| Host | Mouse | 
| Isotype | IgG1 | 
| Immunogen | Peptide | 
| Epitope | a.a. 198 - 212 | 
| Relevance | The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subnit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits. | 
| Specificity | stxA2 | 
| Reported Reactivity | Unknown | 
| Reported Applications | Unknown | 
			
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